AFP Polyclonal Antibody (X-AB-10000)

Storage

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Abbre

AFP

Calculated MW

69 kDa

Host

Rabbit

Synonyms

AFPD, Afp, Alpha fetoglobulin, Alpha fetoprotein, Alpha fetoprotein precursor, Alpha-1-fetoprotein, Alpha-fetoglobulin, Alpha-fetoprotein, FETA, HPAFP, Hereditary persistence of, Hereditary persistence of alpha fetoprotein, alpha-fetoprotein, included

Research Areas

Cancer, Cardiovascular, Developmental Biology

Buffer

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Isotype

IgG

Swissprot

P02771

Conjugation

Unconjugated

background

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Cellular Localization

Secreted

Shipping

The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Concentration

0.5 mg/mL

Clonality

Polyclonal

Applications

WB, IHC

Dilution

WB 1:1000-1:5000, IHC 1:50-1:200

Purification Method

Affinity purification

Reactivity

Human

Immunogen

Recombinant protein of human AFP